This collection includes correspondence, research data, reviews of grant proposals, organizations participated in, laboratories worked for, and student recommendations. The correspondence in the collection dates primarily to the 1960s-70s, when Mildred Cohn worked at the University of Pennsylvania and at the Institute for Cancer Research in Philadelphia, later renamed, Fox Chase Cancer Center. The letters are professional in content, discussing biochemistry, molecular biology, nuclear magnetic resonance (NMR) experiments. The letters also concern lectures and participation in conferences and symposia, and there are materials relating to recommendations for students and colleagues for positions and promotions. Dr. Cohn's interest and involvement in the issue of women in science is presented, of particular note, her work with the University of Pennsylvania's Gender Equity Committee. The notebooks, by Cohn, her colleagues and students, contain extensive experimental data.

This collection includes correspondence, manuscripts (lectures and articles), research grant material, research data, and participation in organizations, such as, the American Society of Naturalists (President, 1968), Genetics Society of America (President, 1963), and the National Research Council. Of particular note, are the detailed data related to Drosophila eye pigment, and human chromosomes.